The following businesses comprise the largest private sector employers in Forsyth County.
| Company | # of Employees | Industry | Origin | Headquarters |
|---|---|---|---|---|
| Northside Hospital Forsyth | 3,100 | Healthcare | USA | |
| Tyson Foods, Inc. | 1,100 | Manufacturing | USA | |
| Scientific Games International, Inc. | 1,000 | Manufacturing / Technology | USA | |
| Koch Foods | 1,000 | Manufacturing | USA | |
| Siemens Industry, Inc. | 700 | Manufacturing | Germany | |
| Solvay Specialty Polymers, LLC | 450 | Manufacturing / R&D | Belgium | YES |
| CommScope, Inc. | 400 | Manufacturing | USA | YES |
| America BOA, Inc. | 350 | Manufacturing | Germany | |
| L3 Harris Technologies, Inc. | 350 | Manufacturing / Technology | USA | |
| AutomationDirect | 280 | Distribution / R&D | Japan | YES |
| BTD Manfacturing | 250 | Manufacturing | USA | |
| Manufacturing Resources International | 250 | Manufacturing | USA | |
| Bako Diagnostics | 235 | Manufacturing | USA | |
| Hansgrohe, Inc. | 220 | Manufacturing | Germany | YES |
| Specialty Appliances, Inc. | 185 | Manufacturing | USA | YES |
| HPI Direct, Inc. | 175 | eCommerce | USA | YES |
| Thermo Fisher Scientific, Inc. | 165 | eCommerce | USA | |
| Chestnut Ridge Nursing & Rehab Center | 165 | Healthcare | USA | YES |
| Benson Integrated Marketing Solutions | 165 | Manufacturing | USA | YES |
| Panduit Corp. | 160 | Manufacturing | USA | |
| Smithfield Foods, Inc. | 150 | Food Packaging | USA | |
| MDSi, Inc. | 140 | Technology | USA | YES |
| American BOA | 140 | Manufacturing | USA | |
| Chemence, Inc. | 130 | Chemicals / Manufacturing | USA | |
| Beaver Toyota | 130 | Motor Vehicle Dealer | USA | |
| Assembleon America | 126 | Manufacturing | ||
| River Valley Ingredients | 122 | Manufacturing | USA | |
| Encompass Health | 120 | Healthcare | USA | |
| Metcam | 120 | Manufacturing | USA | YES |
| Empire Office | 115 | Manufacturing/Furniture | USA | YES |
| Lonza | 115 | Chemicals | USA | |
| CIOX Health | 100 | Healthcare | USA | |
| Sawnee EMC | 100 | Electric Services | USA | YES |
| TN Americas Holding | 100 | Manufacturing | USA |